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CIM 0216
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CIM 0216图片
CAS NO:1031496-06-6
包装与价格:
包装价格(元)
10mg电议
50mg电议

产品介绍
CIM 0216 是一种合成的 TRPM3 配体,是一种有效的选择性 TRPM3 激动剂。
Cas No.1031496-06-6
Canonical SMILESO=C(NC1=NOC(C)=C1)C(C2=CC=CC=C2)N(CCC3)C4=C3C=CC=C4
分子式C21H21N3O2
分子量347.41
溶解度DMSO: slightly soluble,Methanol: slightly soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Selective TRPM3 agonist. Exhibits selectivity for TRPM3 over TRPM1, TRPM2 and TRPM4-8. Stimulates insulin release from pancreatic islet cells in vitro. Evokes nocifensive behavior in mice.

Held et al (2015) Activation of TRPM3 by a potent synthetic ligand reveals a role in peptide release. Proc.Natl.Acad.Sci.U.S.A. 112 E1363 PMID:25733887