Cas No. | 1155-40-4 |
别名 | 4-(4-羟基苯氧基)-3,5-二碘-苯基-乙酸 |
化学名 | 4-(4-hydroxyphenoxy)-3,5-diiodo-benzeneacetic acid |
Canonical SMILES | OC(CC1=CC(I)=C(OC2=CC=C(O)C=C2)C(I)=C1)=O |
分子式 | C14H10I2O4 |
分子量 | 496 |
溶解度 | DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:2): 0.33 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | 3,5-Diiodothyroacetic acid (diac) is the acetic acid variant of thyroxine. Formulations containing dosages in the range of 100 mg/day decrease serum cholesterol and produce calorigenic effects in humans. Formulations containing diac also protect human LDL cholesterol from oxidation in vitro. Diac treatment prevents elevated liver cholesterol in rats fed a high-fat diet and reduces previously elevated liver cholesterol to control levels. |