CAS: | 1093108-50-9 |
分子式: | C25H26F3N5O3 |
分子量: | 501.50 |
纯度: | >98% |
溶解性: | DMSO |
存储: | 4℃, protect from light. In solvent : -80℃, 6 months; -20℃, 1 month (protect from light) |
研究领域: | Inflammation/Immunology Endocrinology |
Target: | hCRTH2:4.5 nM (IC50, in CRTH2 transfected cells) |
描述: | BI-671800 is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2), with IC50 values of 4.5 nM and 3.7 nM for PGD2 binding to CRTH2 in hCRTH2 |