protoporphyrin IX

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protoporphyrin IX

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:	553-12-8
包装:	100mg
市场价:	500元

产品介绍

化学性质

Physical Appearance	A solid
Storage	Store at -20°C
M.Wt	562.66
Cas No.	553-12-8
Formula	C₃₄H₃₄N₄O₄
Solubility	insoluble in H2O; insoluble in EtOH; insoluble in DMSO
Canonical SMILES	O=C(CCC1=C2/C=C3C(CCC(O)=O)=C(C(/C=C(C(C)=C/4C=C)\NC4=C/C5=N/C(C(C=C)=C5C)=C\C(N2)=C1C)=N/3)C)O
运输条件	蓝冰运输或根据您的需求运输。
一般建议	为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。

资料参考

Protoporphyrin IX, widely distributed in all living cells in small amounts, is the final intermediate of the heme biosynthetic pathway. Chelation of Protoporphyrin IX with iron forms heme, which is a constituent of hemoproteins that play essential roles in a variety of biological events, such as oxygen transport, cellular oxidations and reductions, electron transport, as well as drug metabolism. Based on its photodynamic effects, Protoporphyrin IX has also been explored for cancer diagnosis and treatment. However, accumulation of Protoporphyrin IX in human porphyrias can lead to a series of symptoms including skin photosensitivity, hepatobiliary damage, biliary stones, and even liver failure.

Reference:

1. Sachar M, Anderson KE, Ma X. Protoporphyrin IX: the Good, the Bad, and the Ugly. Journal of Pharmacology and Experimental Therapeutics, 2016, 356(2): 267-275.