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M-CSF,human recombinant protein
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
M-CSF,human recombinant protein图片
包装与价格：
包装价格(元)
10ug电议
50ug电议
1mg电议

产品介绍

描述

Gene ID:1435Accession #:P09603
Alternate Names:Human M-CSF, M-CSF, MCSF, M CSF, h-M-CSF, rh-M-CSF, recombinant human M-CSF, recombinant M-CSF.
Source:Escherichia Coli.M.Wt:36.8 kDa
Appearance:Lyophilized proteinStorage:Store at -20°C
Formulation:Sterile filtered and then lyophilized from 5 mM Tris, pH 8.0 + 80 mM Arginine.
Solubility:Reconstitute in water to a concentration of 0.1-0.5 mg/ml. The solution can then be diluted into other aqueous buffers and stored at +4°C for 1 week and -20℃ for future use.
Shipping Condition:Gel pack.Handling:Centrifuge the vial prior to opening.
Usage:For Research Use Only! Not to be used in humans.

资料参考

Macrophage Colony stimulating Factor (M-CSF) is a hematopoietic growth factor produced by lymphocytes, monocytes, fibroblasts, macrophages, bone marrow stromal cells and endothelial cells. M-CSF plays important roles in regulating cell proliferation, differentiation, and survival of blood monocytes, tissue macrophages and their respective progenitor cells. M-CSF also enhances macrophage killing of tumor cells and microorganisms, regulates the release of cytokines from macrophages. MCSF plays critical roles in bone metabolism, immunological defenses, lipoproteins clearance, fertility and pregnancy.

The human M-CSF cDNA encodes a 554 aa protein contains a 32 aa signal sequence. Human M-CSF is active in the mouse, while mouse M-CSF is species-specific. Recombinant human M-CSF is a 36.8 kDa homodimeric protein containing two 159 amino acid polypeptide subunits.

生物活性

Determined by the dose-dependent stimulation of the proliferation of murine M-NSF-60 cells.
ED50< 5.0 ng/ml.     
Specific activity> 2*105units/mg.