| 包装 | 价格(元) |
| 10ug | 电议 |
| 50ug | 电议 |
| 1mg | 电议 |
| Gene ID: | 3600 | Accession #: | P40933 |
| Alternate Names: | Human IL-15, IL-15, IL15, IL 15, h-IL-15, rh-IL-15, recombinant human IL-15, recombinant IL-15, IL, interluekin. | ||
| Source: | Escherichia Coli. | M.Wt: | 12.8 kDa |
| Appearance: | Lyophilized protein | Storage: | Store at -20°C |
| Formulation: | Lyophilized from 5 mM Tris, pH 8.0. | ||
| Solubility: | Reconstitute in H2O to a concentration of 0.1-1.0 μg/μl. The solution can then be diluted into other aqueous buffers and stored at 4℃ for 1 week or -20℃ for future use. | ||
| Shipping Condition: | Gel pack. | Handling: | Centrifuge the vial prior to opening. |
| Usage: | For Research Use Only! Not to be used in humans. | ||
Interleukin 15 (IL-15) is an immunomodulating cytokine mainly produced by adherent peripheral blood mononuclear cells, fibroblasts and epithelial cells and stimulates the proliferation of T lymphocytes. IL-15 shares many biological properties with IL-2, including T, B and natural killer cell-stimulatory activities. IL-15 is essential in the development, survival and activation of NK cells. Increased expression of IL-15 has been implicated with rheumatoid arthritis, inflammatory bowel disease and diseases affiliated with retroviruses.
The human IL-15 cDNA encodes a 162 aa protein with a 29 aa signal sequence and a 19 aa propeptide. Both human and simian IL-15 are active on mouse cells. Recombinant human IL-15 is a 12.8 kDa protein containing 114 amino acid residues.
| Determined by the dose-dependent stimulation of the proliferation of CTLL-2 cells. | ||||||
| ED50 | < 0.5 ng/ml. | |||||
| Specific activity | > 2*106units/mg. | |||||
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