4-Methylumbelliferyl-β-D-N,N',N''-Triacetylchitotrioside

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本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

53643-13-3

包装与价格：

产品介绍

4-Methylumbelliferyl-β-D-N,N',N''-triacetylchitotrioside is a fluorogenic substrate for chitinases and chitotriosidases.

Cas No.	53643-13-3
别名	4-甲基伞形酮基Β-D-N,N`,N``-三乙酰基壳三糖苷
Canonical SMILES	CC(N[C@H]([C@H]1O)[C@H](OC2=CC=C(C(C)=CC(O3)=O)C3=C2)O[C@H](CO)[C@H]1O[C@@](O[C@@H]4CO)([H])[C@H](NC(C)=O)[C@@H](O)[C@@H]4O[C@]5([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5NC(C)=O)=O
分子式	C₃₄H₄₇N₃O₁₈
分子量	785.8
溶解度	DMF: 5mg/mL,DMSO: 10mg/mL
储存条件	Store at -20°C,protect from light
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
产品描述	4-Methylumbelliferyl-β-D-N,N',N''-triacetylchitotrioside is a fluorogenic substrate for chitinases and chitotriosidases. 4-Methylumbelliferyl-β-D-N,N',N''-triacetylchitotrioside is cleaved by chitinases and chitotriosidases to release the fluorescent moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases. It has been used to screen plasma samples for reduced chitotriosidase activity that may be indicative of lysosomal storage disorders.