3-O-Methyl-N-acetyl-D-glucosamine 是 N-乙酰氨基葡萄糖激酶的有效抑制剂。
| Cas No. | 94825-74-8 |
| 别名 | 2-乙酰氨基-2-脱氧-3-O-甲基D-D-吡喃葡萄糖,3-O-Methyl-GlcNAc |
| Canonical SMILES | OC1[C@H](NC(C)=O)C(OC)[C@@H](O)[C@@H](CO)O1 |
| 分子式 | C9H17NO6 |
| 分子量 | 235.2 |
| 溶解度 | DMF: 30 mg/ml,DMSO: 30 mg/ml,PBS (pH 7.2): 1 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 3-O-methyl-N-acetyl-D-Glucosamine (3-O-methyl-GlcNAc) is a competitive inhibitor of N-acetylglucosamine kinase and a non-competitive inhibitor of N-acetylmannosamine kinase (Kis = 17 and 80 µM in rat liver, respectively, in vitro). |
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