AminobenzenesulfonicauristatinE-d8 is the deuterium labeled AminobenzenesulfonicauristatinE. AminobenzenesulfonicauristatinE is a drug-linker conjugate for ADC. AminobenzenesulfonicauristatinE has potent antitumor activity by usingAuristatinE (a cytotoxic tubulin modifier), linked via theADC linkerAminobenzenesulfonic^[1][2].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[2].

761.05

Solid

C₃₇H₅₆D₈N₆O₈S

Room temperature in continental US; may vary elsewhere.

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)