Doxorubicinone 是一种抗癌化疗药物 Doxorubicin 的代谢物。 Doxorubicin 是一种有效的人类 DNA 拓扑异构酶 I 和拓扑异构酶 II 抑制剂，IC50 分别为 0.8 μM 和 2.67 μM。
| Cas No. | 24385-10-2 |
| 别名 | 阿霉酮,Adriamycin aglycone; Adriamycinone |
| 化学名 | (8S,10S)-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione |
| Canonical SMILES | OC1=C(C[C@](C(CO)=O)(O)C[C@@H]2O)C2=C(O)C(C3=O)=C1C(C4=CC=CC(OC)=C34)=O |
| 分子式 | C21H18O9 |
| 分子量 | 414.4 |
| 溶解度 | DMF: 5 mg/ml,DMSO: 5 mg/ml,Ethanol: 5 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Doxorubicinone |
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