| CAS NO: | 54010-71-8 |
| 包装 | 价格(元) |
| 500mg | 电议 |
| 1g | 电议 |
| 5g | 电议 |
| Cas No. | 54010-71-8 |
| 别名 | D-葡萄糖-6-磷酸 |
| 化学名 | sodium ((2R,3S,4S,5R,6R)-3,4,5,6-tetrahydroxytetrahydro-2H-pyran-2-yl)methyl hydrogenphosphate |
| Canonical SMILES | O[C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)O)O)COP(O)([O-])=O.[Na+] |
| 分子式 | C6H12NaO9P |
| 分子量 | 282.12 |
| 溶解度 | 10mg in PBS， pH 7.2 |
| 储存条件 | Store at RT |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | D-Glucose-6-phosphate is formed in cells when glucose is phosphorylated by hexokinase (or glucokinase) or by the conversion of glucose-1-phosphate by phosphoglucomutase, which is the first step of glycogen synthesis.[1] It is stored as glycogen when blood glucose levels are high. Disruption of D-glucose-6-phosphate activity leads to glycogen storage disease type I or von Gierke’s disease, a group of inherited metabolic diseases characterized by severe hypoglycemia, growth retardation, and hepatomegaly, due to accumulation of glycogen and fat in the liver.[2],[3] D-Glucose-6-phosphate is also the starting molecule of both glycolysis and the pentose phosphate pathways.[4] Because cancer cells adopt glycolysis as a major source of metabolic energy production, and the pentose phosphate pathway plays a role in helping glycolytic cancer cells to meet their anabolic demands, this compound can be used to study the progression of this process.[5] Reference: |
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