Elliptinium acetate

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Elliptinium acetate

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

58337-35-2

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品名称

NSC 264137
Celiptium

产品介绍

Elliptinium acetate (NSC 264137) 是一种 DNA 插层剂，对 L1 210 细胞具有较强的细胞毒性，并且能与 L1210 细胞的核酸共价结合。Elliptinium acetate 可用于癌症，尤其是转移性乳腺癌的研究。

生物活性

Elliptinium acetate (NSC 264137) is a DNA intercalating agent that is highly cytotoxic to L1 210 cells and covalently binds to nucleic acids from L1210 cells. Elliptinium acetate can be used incancerresearch, particularly in metastatic breastcancer^[1]^[2].

IC₅₀& Target

Nucleic acids^[1]^[2].

体外研究
(In Vitro)

Elliptinium (0.35 μM; 1 h) (9-OH-NME3) shows highly stable covalent bonding to nucleic acids of L1210 cells^[1].

Cell Viability Assay^[1]

Cell Line:	L1 210 cells
Concentration:	0.35 μM
Incubation Time:	1 h
Result:	Exhibited highly stable covalent bonding to DNA and RNA. Showed no reversal of binding as cells went on replicating during a 40-h period.

分子量

336.38

Formula

C₂₀H₂₀N₂O₃

CAS 号

58337-35-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.