COX-2/PI3K-IN-2 (compound 5f) is a potentPI3Kinhibitor withIC₅₀value of 2.78 nM. COX-2/PI3K-IN-2 is a selectiveCOX-2inhibitor withK_ivalue of 3.02 nM. COX-2/PI3K-IN-2 shows anti-inflammatory and anti-cancer properties^[1].

COX-2/PI3K-IN-2 (compound 5f) (50-500 μg/mL, 72 hours) exerts potent antitumor activities against Breast cancer (MCF-7) cells^[1].
COX-2/PI3K-IN-2 (compound 5f) (10-150 μg/mL) has antioxidant properties with H_{2O2scavenging activity equivalent to ascorbic acid and higher lysozyme inhibition (IC50=3.25 nM)^[1].}

311.34

C₁₆H₁₇N₅O₂

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.